Double translocation heterozygotes (DTH) involving all 3 chromosomes were obtained in Aedes aegypti (L.) by 2 methods of crossing translocation heterozygotes. The average fertility of 7 different DTH males was 23.6 percent. DTH breeding schemes, utilizing translocation heterozygotes, are discussed in relation to utilization of conditional lethals for separating genetic types and inversions for stabilizing desirable genotypes.