A total of 1,480 Anopheles gambiae sensu lato and 439 An. .funestus, collected from 30 sitesalong the Kenyan coast, were tested by direct enzyme-linked immunosorbent assay (ELISA) for blood-mealidentification. Overall, the enzyme-linked immunosorbent assay (ELISA) identified 92 and 87% of the samplestested in An. gambiae s.1. and An. funestus, respectively. Of these, human IgG was detected in 98.97% (n =7,347)of An.gambiaes.l.and,99.48Vo(n:379)of An.funestus.Only14(l.O3qo) oftheAz. gambiaes.l.hadfed on other vertebrate hosts tested, which were bovines, chickens, and goats. Additionally, only 2 An. funestushad fed on goats. In all the 28 sites that had bloodfed mosquitoes, An. gambiae s.l. had a human blood indexgreater than 0.9. Twenty-five of these sites had a human blood index greater than O.9 for An. funestus, whilethe other 3 sites had no bloodfed mosquitoes. The An. gambiae s.l. were tested by polymerase chain reaction(PCR) for species identification. A total of 338 were An. gambiae s.s., 79 were An. arabiensis, and 12 were An.merus. Tlre human blood index was 0.96, 0.91, and 1.0 for An. gambiae s.s., An. arabiensis, and An. merus,respectively. The Plasmodium falciparum sporozoite infection rates were 6.2% for species in the An. gambiaecomplex and 3.7Vo for An. funestus. These results emphasize that An. funestus and members of the An. gambiaecomplex on the Kenyan coast are highly anthropophilic, with nearly all specimens feeding on humans duringevery blood meal. The results further demonstrated active transmission of P. falciparum sporozoites by theprimary vector species. This study suggests that the use of insecticide-treated nets will be effective for controllingbiting mosquitoes inside houses along the coast of Kenya.