Sixteen commercial insect repellents (6 botanical and 10 synthetic organic products) in sprayformulations were evaluated in the laboratory for adult knockdown (KD) and mortality of laboratory-rearedfemale Aedes aegypti, Aedes albopictus, and Anopheles quadrimaculatus. All tested products produced significantposttreatment KD and 24 h mortality of all 3 mosquito species. ln our study, the synthetic organic repellentsinduced faster KD and KD of higher magnitude in adult mosquitoes than the botanical product repellents exceptgeraniol-based MosquitoSafe™. All tested formulations except 2 botanical repellent products caused 100% 24-h mortality of Ae. aegypti and all but 1 caused 100% 24-h mortality of Ae. albopictus and An. quadrimaculatus.