The efficacy of synthetic pyrethroid-impregnated fabrics was evaluated against Anopheles stephensi, Aedes aegypti, and Culex quinquefasciatus, under laboratory conditions. Results revealed that delta-methrin was significantly superior in comparison to lambdacyhalothrin and cyfluthrin. Results of bioassay tests revealed that deltamethrin was 1.5 and 1.9 times more effective than lambdacyhalothrin and cyfluthrin, respectively, against An. stephensi exposed to cotton fabric treated at 100 g/m2. Deltamethrin was 3.9 and 4.6 times more effective against Ae. aegypti and 3.53 and 4.0 times more effective against Cx. quinquefasciatus. Of cotton, nylon, polyethylene, and jute fabrics, the cotton was the best on the basis of median lethal dose (LD50) and 95% lethal dose (LD90) values and persistence of insecticide.